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(−)-Cannabidiol (CBD) is a non-psychotropic component of Cannabis with possible therapeutic use as an anti-inflammatory drug. Little is known on the possible molecular targets of this compound. We investigated whether CBD and some of its derivatives interact with vanilloid receptor type 1 (VR1), the receptor for capsaicin, or with proteins that inactivate the endogenous cannabinoid Cannabinoids suitable for migraine prevention Jun 29, 2017 · The results after three months of treatment and follow-up after a further four weeks produced various insights. While the TCH-CBD combination yielded slightly better results than amitriptyline (40.1%) with a 40.4% reduction in attacks, the severity and number of cluster headache attacks only fell slightly. CBDV Shows Promise Relieving Seizure Activity
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